stray musings and introspections stumbled upon in the stacks or the recovery period thereafter
Wednesday, May 31, 2006
What is/are your biggest strength/s? or the good the bad and the ugly
Saturday, May 27, 2006
what is a rogue economist--and is that anything like a rampaging librarian?
Friday, May 26, 2006
Crying into the Floor
smell of Beer Soaked Air
Empty Cans,
Half Empty Cans,
Full Cans
moving, knocking, falling
with any movement
which is difficult
Anyway
wedged between a coffee table
and Someone's back
not enough warmth
not enough clothing
not enough knowledge
(or too much)
laughing, crying, shrieking,
Something
Large and Shuddering
Into the Floor
to Muffle the sound
breathing Beer
so much Beer
and not having
Drunk
crying into the Floor
Someone else's Floor.
and Before
it was
Please, Please, Please
Please
it was
Love me
Please Love me
Somehow
it was
wondering
and pain
and ecstasy
it was Please
and biting back tears
and biting back pleasure
it was biting back
and holding in
it was so much
and too full
and on the verge
and it was Please
and it was
Why and
How
and it was
Please
it was almost
Tears and it was almost
Something else
it was almost.
and before
it was getting off early
and sitting at His table
and driving in my car
and sitting on Someone's floor
and moving to the couch
and not speaking and
Not leaving
and being left to
Crash
on Someone else's floor
But
Somewhere
Between the lines
it progressed
and I did not see the
Movement
but I felt it
and it was conversations with the Mirror
in the Bathroom
and it was thinking
No, No, No
while
my body braced
and it was knowing
and wanting
and not wanting
and it had
Been so Long
and it was happening
and it was No
and Please
Please, Please
and almost tears
and after
it was
crying into the Floor
and after
it was wondering
and praying for sleep
and after
it was renewal
and After
it was
"What are you doing here?"
and it was
"sleeping on your floor."
and it was confusion
and it was almost tears
and it was
Someone else's house.
and I cannot wish it did not happen
but I can want More
and it is Please
Please, Please...
Wednesday, May 24, 2006
FDA caves to political pressure: or whatever happened to medical science?
Medical Marijuana: Politics Trumps Science at the FDA
Posted 05/17/2006
by Gregory T. Carter, MD; Bruce Mirken
For a Food and Drug Administration (FDA) increasingly mired in controversies over the politicization of scientific and regulatory decisions, the agency's April 20, 2006 statement regarding medical use of marijuana may represent an all-time low point. Politics, it appears, has now completely trumped science at this once proudly independent agency. The FDA has announced that "no sound scientific studies" support the medical use of marijuana, contradicting an increasingly large body of scientific literature. To those of us who do research in this area, this is a personal affront. Even the federal Drug Enforcement Agency's (DEA) own Administrative Law Judge, the Honorable Francis Young, stated in 1988, "Marijuana is the safest therapeutically active substance known to man..." He went on to say, "The evidence clearly shows that marijuana is capable of relieving the distress of great numbers of very ill people, and doing so with safety under medical supervision. . .it would be unreasonable, arbitrary and capricious for the DEA to continue to stand between those sufferers and the benefits of this substance." Perhaps more remarkable were the conclusions of President Nixon's Shafer Commission, who were appointed to investigate marijuana's available scientific and medical evidence. To the shock and dismay of President Nixon, the Commission found enough evidence to recommend that marijuana be decriminalized. The FDA's announcement is puzzling at many levels. It makes no mention of any recent FDA analysis or investigation, regulatory filing, or any other activity within the normal scope of the agency's work that led to this policy change. Thus, there is no indication as to why the agency chose to issue this opinion at this particular moment. Rather than being based on new data or analysis, the statement appears to have been issued in response to the repeated requests from US Rep. Mark Souder (R-IN), a vehement opponent of medical marijuana use. Souder wrote to acting FDA Commissioner Andrew C. von Eschenbach on January 18, 2006, saying, "I am exasperated at the FDA's failure to act against the fraudulent claims about 'medical' marijuana." He urged that the FDA "post accurate information about the claims of 'medical' marijuana on its website." After 2 months he renewed the request, taking an impatient tone: "I have yet to receive a response from the Food and Drug Administration regarding my January 18, 2006 letter to you about the FDA's failure to provide any meaningful information on its website about the dangers of marijuana. I am quite concerned that the FDA does not take seriously the threat posed by marijuana, our nation's most abused drug." The FDA's missive appears to be just what Souder wanted; it asserts that there is a lack of evidence regarding the medical value of marijuana and argues that state laws permitting medical use of marijuana without criminal penalty "are inconsistent with efforts to ensure that medications undergo the rigorous scientific scrutiny of the FDA approval process." The statement concludes by saying that the FDA, along with 2 nonmedical agencies, the DEA and the White House Office of National Drug Control Policy, "do not support the use of smoked marijuana for medical purposes."
We beg to differ with Mr. Souder, who, to our knowledge has no scientific background or medical training. The scientific studies that document the medical efficacy and safety of smoked marijuana are published in peer-reviewed medical journals and are available through the National Library of Medicine. In our experience, the medical peer-review process is very harsh and stringent. Thus, it is not likely that the hundreds of peer-reviewed scientific articles published documenting the benefits of marijuana contain "fraudulent claims."
Moreover, maybe the FDA and Mr. Souder are not aware that The National Institutes of Health (NIH) and the Institute of Medicine have previously issued statements of support for medical marijuana and have called for further investigation. The Institute of Medicine reviewed the issue a second time at the request of the White House Office of National Drug Control Policy, resulting in a 1999 report which declared, "Nausea appetite loss, pain and anxiety are all afflictions of wasting, and all can be mitigated by marijuana."
While expressing concern over the risks of smoking, the Institute noted that for some patients -- particularly those with terminal conditions or who do not respond to standard therapies -- those risks would be "of little consequence." The report added pointedly, "We acknowledge that there is no clear alternative for people suffering from chronic conditions that might be relieved by smoking marijuana, such as pain or AIDS wasting."
This was, in fact, the prior stance taken by the FDA itself, before this sudden turnaround. Perhaps the FDA has forgotten that doctors can prescribe dronabinol (Marinol), which is 100% pure synthetic delta(9)-tetrahydrocannabinol (THC). This is the most powerful psychoactive compound in marijuana, and it is placed in the same category as the prescription strengths of ibuprofen, meaning a physician can phone in the prescription. Furthermore, the recent discovery of an endogenous cannabinoid system with specific receptors and ligands has increased our understanding of the actions of marijuana. The cannabinoid system appears to be intricately involved in normal human physiology, specifically in the control of movement, pain, memory and appetite, among others. Widespread cannabinoid receptors have been discovered in the brain and peripheral tissues. The cannabinoid system represents a previously unrecognized ubiquitous network in the nervous system.
There is a dense receptor concentration in the cerebellum, basal ganglia, and hippocampus, accounting for the effects on motor tone, coordination, and mood state. There are very few cannabinoid receptors in the brainstem, which may explain marijuana's remarkably low toxicity. There has never been a lethal overdose of marijuana reported in humans. In addition, we have shown that marijuana can be dosed, much like other prescribed drugs. Moreover, in some instances patients report it as more therapeutic and better tolerated than other medications.
Despite all of this scientific documentation, following the recent Supreme Court ruling [Gonzales v. Raich], Drug Czar John Walters commented, "The medical marijuana farce is done." He then added, "I don't doubt that some people feel better when they use marijuana, but that's not modern science. That's snake oil." But isn't the very definition of palliative care the abatement of suffering in order to make patients "feel better"? Isn't that what doctors and other health professionals are supposed to do for a living?
In what appears to be an effort to justify the issuance of a statement on medical marijuana with no evident scientific or regulatory reason to do so, the FDA misrepresents the nature and purpose of state medical marijuana laws, stating, "A growing number of states have passed voter referenda (or legislative actions) making smoked marijuana available for a variety of medical conditions upon a doctor's recommendation," suggesting that such laws "seek to bypass the FDA drug approval process." If that were the case, the FDA might arguably have an interest in opining about such laws. But as a general rule, the 11 state medical marijuana laws do not make marijuana available or in any way address the issue of marketing or sales. Rather, they simply protect patients who meet certain conditions (usually including a physician recommendation and/or diagnosis with a qualifying condition) from arrest and punishment under state laws that otherwise forbid marijuana possession or cultivation, Indeed, the lack of a legal means for patients to obtain marijuana for medical use has been a source of controversy in some states that have adopted medical marijuana laws.
One wonders: Does the FDA not understand the difference between licensing a drug for marketing and simply choosing not to arrest individuals who possess that drug under certain conditions? Does the agency believe that arrest and imprisonment are appropriate ways of dealing with a patient's choice to self-treat with an herbal product not approved as a medicine by the FDA?
The recent change of heart by the FDA is disappointing on many levels. This is certainly not the first time the FDA has been accused of letting politics trump science. However, it is the duty of the FDA to be an impartial scientific body and not rent itself out to political agendas. Arguably, marijuana is neither a miracle compound nor the answer to everyone's ills. Yet it is not a compound that deserves the tremendous legal and societal commotion that has surrounded its use. Over the past 30 years, the United States has spent billions in an effort to stem the use of illicit drugs, including marijuana, with limited success. Some very ill people have had to fight long court battles to defend themselves for having used a compound that has helped them. There is no evidence that recreational marijuana use is any higher in states that allow for its medicinal use. Moreover, prohibition strategies have never proven terribly effective at limiting the use of a substance - whether it be alcohol or other compounds -- for any reason.
Rational, apolitical minds need to take over the debate on marijuana, separating myth from fact, right from wrong, and responsible, medicinal use from other, less compelling usages. However one feels about nonmedical use of marijuana, in our opinion, the medicinal marijuana user should not be considered a criminal in any state. The scientific process continues to document the therapeutic effects of marijuana through ongoing research and assessment of available data. With regard to the medicinal use of marijuana, our federal government and legal system should take a similar approach, using science and logic, rather than politics, as the basis of policymaking. This recent change of policy by the FDA, with politics apparently taking precedence over science, is disappointing and unwarranted.
"Alcohol thus ranks at the dangerous end of the toxicity spectrum. So despite the fact that about 75 percent of all adults in the United States enjoy an occasional drink, it must be remembered that alcohol is quite toxic. Indeed, if alcohol were a newly formulated beverage, its high toxicity and addiction potential would surely prevent it from being marketed as a food or drug. This conclusion runs counter to the common view that one's own use of alcohol is harmless. That mistaken impression arises for several reasons."
"What people frequently do not realize is that the cigarette is a very efficient and highly engineered drug-delivery system. By inhaling, the smoker can get nicotine to the brain very rapidly with every puff. A typical smoker will take 10 puffs on a cigarette over a period of 5 minutes that the cigarette is lit. Thus, a person who smokes about 1-1/2 packs (30 cigarettes) daily, gets 300 "hits" of nicotine to the brain each day. These factors contribute considerably to nicotine's highly addictive nature."
Anyway i sense a bit of rant boiling up and since it is still my birth month and therefore the season of the rampaging taurean, maybe i should step off my soapbox get back to my original task...
Monday, May 22, 2006
i am drowning in Stuff
Why do (some of us) seem to hang on to so much? I know that at least part of my reasoning is that if i hang on to THINGS i can hang on to the feelings or memories attached to them, but is that really true?
Friday, May 19, 2006
Every man's an island
conspiracy theory anyone?
Thursday, May 18, 2006
who would have thought?
Ursula the wise
Wednesday, May 17, 2006
Don't Read This
Saturday, May 13, 2006
everything that rises must converge
our mothers/ourselves
and i'm not even sure we were having an argument. I won't even try to go into details because it is too much and too little just suffice it to say she was being maternal and i was being childish or something like that.
and now i'm smoking a cigarette (a stale clove cigarette, contraband in this state, i don't smoke, but i had i craving, plus there's the rebellion issue...) i had been driving home from a lovely evening out with friends and had been thinking of buying one of those single cigarettes but decided against it in a fit of adultness and look at me now.
Friday, May 12, 2006
what time does your clock say?
Thursday, May 11, 2006
you say it's your birthday; it's my birthday too... yeah!
And did i mention that my youngest cat, Demetra, had her first birthday today as well
Monday, May 08, 2006
how many books are there in a trilogy, anyway?
Sunday, May 07, 2006
so today I was shushed
in the waning hours (before the end)
And if so when will you leave me?
What are the stories you will tell me before you go?
Is it the stories i receive comfort from?
The times you rock me in you arms,
back and forth across the floor,
stories about old shep –i think he’s dying–think he’s leaving in the end
stories about monk-the-monk (that’s me) monk the monk- doesn’t he fall to his knees in the end–no support
but old shep–there was always old shep whatever it was about old shep did he get shot did he go out to pasture i have no memory of ol shep he was just a good ol boy who went the god ol way and i don’t know anything but i was beginning to know something i was beginning to hear things i tried not to hear i just wanted to go to hawaii and we went to hawaii and it was christmas and everything was cool in hawaii and i found a friend and we tried to hide in the ocean but the ocean tumbles and tosses us a bit more than is comfortable for me it is my cradle and my grave–always has been love the sea–the salt–the blood–the life–the time–the tide WHAT DOES THAT TIKI REPRESENT my parents went to hawaii to celebrate their divorce HAHAHA where am i now?
LOST
playing games with scent fire pain death alcohol drugs
where does it end
who am i
who are you?
Strange stories on gender
who are we
still trying to thread the wick through the candle
honk honk beep beep
i don’t want to be 39
don’t feel 29
what is age
is there anyone alive who can tell me who i am.????
...i need your love